The accomplice who secretly raises your uric acid is not high-purine foods, but this kind of thing you love to eat

Uric acid is a metabolite that exists in the body, and under normal circumstances, the human body produces 600mg of new uric acid every day, and eliminates 600mg to maintain a balance.

Uric acid is measured in the blood, called the blood uric acid level, and is an indicator of whether uric acid is elevated. Of course, uric acid levels can also be measured in urine, but it is mainly used to determine the ability of the kidneys to excrete uric acid.


At present, the normal standard range of blood uric acid level in China is μmol/L, between 178~416 for men and 148~357 for women, that is to say, if it exceeds 416μmol/L for men and 357μmol/L for women, it can be diagnosed as "hyperuricemia".


Uric acid is not only related to the purines ingested

 

If the human body is compared to a factory, uric acid is like a waste from industrial production, the liver in the human body will process useless purines into uric acid, and then excrete uric acid through detoxification organs such as kidneys and intestines, and the whole process is within a stable range.


If something goes wrong here, uric acid may rise. To put it simply, if uric acid rises, either you eat more purines or you excrete less uric acid.


The excretion of uric acid is less, which is greatly affected by genetic factors, and the problem of excessive purine intake is partly related to diet, which is why people with gout and hyperuricemia are recommended to control purine intake.


But another major source of purines, many people are not clear, that is, our body produces its own purines, although some foods do not contain purines, but some of the components it contains can promote the body to synthesize more purines, resulting in an increase in uric acid.


The "accomplice" of high uric acid: fructose


The uric acid in the body is too high, which is easy to cause the danger of gout, and many people will strictly follow the high-purine food list to control their diet, so the problem is that some people obviously do not eat seafood, drink thick soup and other high-purine foods, and also quit smoking and drinking, but uric acid has remained high.


When it comes to eating, it's right to eat less seafood and drink less beer, but many people tend to overlook another important detail: fructose!


The effects of fructose on gout have been discovered in recent years, and a study in the British Medical Journal found that the intake of sugary soft drinks and fructose-rich water and fruit juices is closely related to an increased risk of gout.


Recent studies have also found that the intake of high-fructose beverages is parallel to the increase in the incidence of gout, and in addition, it has also been found that fructose can increase appetite and is not regulated by insulin and leptin, so the eater will not feel full.


Therefore, fructose is listed as an important risk factor for common complications or comorbidities of gout such as diabetes, hypertension, and fatty liver.


Among them, sugary drinks are typical representatives. Fructose is associated with an increase in uric acid, and after entering the body, it participates in metabolic processes and promotes purine synthesis, resulting in increased uric acid production.


Many patients with high uric acid are unaware of the dangers of sugary drinks, and may even feel that replacing alcohol with drinks is a more "healthy" dietary choice, which really outweighs the benefits.


Special attention should be paid to these "fructose" foods


1. Any sweet drinks: All kinds of sweet drinks sold on the market, including carbonated drinks, fruit juices, so-called functional drinks, etc., are one of the richest sources of fructose, and gout patients should be cautious about drinking.


2. Honey: Although honey has high nutritional value, its fructose content is as high as 70%, and gout patients must eat it sparingly.


3. Fruits with more fructose content: The mangoes, lychees, cantaloupe, watermelons, melons, etc. that we usually eat are fruits with high sugar content.


There are also some fruits that are hidden sources of fructose, such as citrus, peaches, plums, apricots, etc., which contain more sucrose, and half of them will be converted into fructose after catabolism, which also needs attention.


Fruits are nutritious, and there is no problem with controlling them within 500g a day, but don't be greedy.


4. Baking pastries: doughnuts, biscuits, cakes, brownies, croissants and other bread and pastries that everyone loves are high-sugar foods, pay attention not to eat too much, in case uric acid increases.


5. All kinds of syrup: corn syrup, corn sweetener, etc., these syrups contain high fructose, so they are often used instead of sugar, and are most commonly used in making desserts.


The last two points are important


1. Drink more water and quit drinking: Drink more than 1500ml a day, drink water to promote body metabolism and urination, and help the body excrete uric acid. Quit alcohol, alcohol has the effect of inhibiting the excretion of uric acid, so it is necessary to prohibit drinking beer and liquor.


2. Insist on exercising and controlling weight: Do moderate-intensity exercise for about 30 minutes a day, pay attention to avoid strenuous exercise or injury, and obese people should lose weight to control their weight within the normal range.


High uric acid is harmful not only for gout


Many people still only stop at the consequences of hyperuricemia, but in reality, it can be far more harmful than you think.


01. Joint damage


Gouty arthritis usually causes sudden, severe pain in the first metatarsophalangeal joint, ankle joint, dorsum of the foot, and knee joint, with redness and swelling in the joints within a few hours of onset.


In most cases, only one joint attacks, but some people also affect more than one joint, urate crystals are deposited in the joints, and the crystals can stimulate the joints to produce inflammation, causing tophi, gout bone destruction, etc.


02, hyperuricic acid nephropathy


Gout occurs in only about 10% of people with hyperuricemia, which is also associated with damage to a variety of organs, such as uric acid nephropathy.


Normal human uric acid production and clearance maintain a homeostasis. Excessive uric acid formation or impaired excretion can produce hyperuricemia, and high uric acid in the blood will increase the burden on the kidneys, resulting in high uric acid in the urine, which will cause urate to be deposited in the kidneys, resulting in uric acid nephropathy.


In addition, high uric acid also greatly increases the risk of developing a variety of metabolic-related diseases (such as diabetes, hyperlipidemia, etc.) and cardiovascular diseases.